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The normal function of the articular cartilage is to protect the bones and to ensure that the forces slide and dampen during loading. The articular cartilage is constantly exposed to mechanical pressures, which are necessary for its health. The loss of the ability to respond to stress and the metabolic changes caused by them, leads to degeneration as observed in OA.
Cartilage is made up of chondrocytes, intercellular substance, collagen fibers and proteoglycans.
Synovial fluid is a yellowish viscous fluid that fills the synovial cavity. It is a plasma ultrafiltrate containing various substances and hyaluronic acid. Its main functions are nutritional support and lubrication of cartilage and shock absorption. The action of synovial fluid as a shock absorber protects the cartilage and bones from the pressures that develop when we move, walk, run, etc.
Hyaluronic acid is produced by chondrocytes and synovial cells and is released by them into the synovial cavity. It penetrates the surface layer of cartilage and synovial membrane creating a protective layer against mechanical injuries and chemical irritations.
In the case of osteoarthritis, the elasticity and viscosity of synovial fluid is significantly lower compared to a normal joint. An important reason is the reduction of the molecular weight and concentration of hyaluronic acid, resulting in a reduction of its "lubricating" and protective effect. When this is reduced, the pressures of weight as a result of normal movement, cause damage to the surface of the cartilage and the synovial membrane.
The enhancement of viscoelasticity with hyaluronic acid is a safe, effective and established option in the treatment of osteoarthritis symptoms and consists of injecting a hyaluronic acid solution into the affected joint.
Exogenous administration of hyaluronic acid activates the cells of the synovial membrane to produce normal hyaluronic acid and provides the structural skeleton of proteoglycans. At the same time, the inflammation cells are reduced and the free radicals and peroxides are controlled.
Chondryal plus is a product for enhancing viscoelasticity that contains a unique combination of Sodium hyaluronate 60mg / 3ml and Chondroitin sodium sulphate 90mg / 3ml in a pre-filled syringe. The combination is unique and is the first to be released in Greece. The estimated duration of action of Chondryal plus is about one year.
Sodium hyaluronate provides symptomatic relief of osteoarthritis by restoring the viscosity of synovial fluid and stimulating the production of hyaluronic acid by the synovial membrane.
Chondroitin sulfate is fundamental to the structural and functional integrity of joints since it makes up the majority of the glycosaminoglycans of articular cartilage. Chondroitin sulfate stimulates the synthesis of proteoglycans by chondrocytes and inhibits the production of substances that prematurely degrade cartilage. It also stimulates the synthesis of high molecular weight hyaluronic acid.
The unique combination of the two substances can further improve the therapeutic effectiveness and offers:
EAN: 5944728003231
