Doctor's Formulas Inositol Formula Inositol 60 Tablets

Inositol Formula is a dietary supplement containing inositol, folic acid, vitamin B6 and vitamin B12.

These components contribute to the normal functioning of the immune and nervous systems, as well as to normal psychological function. 

A few words about the biochemical action of Inositol

More specifically, inositol is known as vitamin B8, a natural isomer of glucose. It is an important intermediate key element of the second messengers, but also a dominant component of the phospholipids of cell membranes involved in many biological processes.

It is a component of the biological information exchange system.

Η inositol contributes to the processing of information inside the cell, e.g. of the biological information contained in hormones. Second messengers are molecules inside cells that act to transmit signals from a receptor to a target. The term, second messengers, was coined after the discovery of these substances, in order to distinguish them from hormones and other molecules that function outside the cell as "first messengers" in the transmission of biological information. A large number of molecules have been characterized as second messengers, including molecules derived from phospholipids. (inositol triphosphate).

A general second messenger mechanism can be divided into four stages.

• First step: the agonist activates a membrane-bound receptor.
• Second stage: the activated G protein produces a core effector.
• Third stage: the main effect stimulates the synthesis of the second messenger.
• Fourth stage: the second messenger activates a certain cellular process.

G-protein-coupled receptors for the PIP2 system (phosphatidyl-inositol diphosphate) messenger, produces two effectors, phospholipase C (PLC) and phosphoinositide 3-kinase (PI3K). PLC as an effector produces two different second messengers, inositol triphosphate (IP3) and diacylglycerol (DAG).

Η (inositol triphosphate) IP3 is soluble and freely diffuses into the cytoplasm. As a second messenger, it is recognized by the inositol triphosphate receptor (IP3R), a Ca2+ channel in the endoplasmic reticulum (ER) membrane, which stores intracellular Ca2+.

Binding of IP3 (inositol triphosphate) to its receptor releases Ca2+ from the endoplasmic reticulum into the normally Ca2+-poor cytoplasm, which then activates various Ca2+ signaling events. Specifically in blood vessels, the increase in Ca2+ concentration from (inositol triphosphate) IP3 releases nitric oxide, which then diffuses into the smooth muscle tissue and causes relaxation.

In 1984, with a paper published in Nature, inositol triphosphate was officially classified as the second messenger of cell signaling. Until 2010 the volume of the bibliography exceeds 20.000 publications in many scientific journals.

Her role starts from biology, she is involved in medicine (in specialties such as neurology, endocrinology and pathology), and is carried out in pharmaceuticals.

Suitable for vegetarians

EOF Notification Number: 16897 / 15-02-2016

(The Notification Number to the EOF is not a marketing authorization from the EOF)

EAN: 5200403400222

Other ingredients: Dicalcium Phosphate, Microcrystalline Cellulose, Maltodextrin, Precipitated Silica, Vegetable Magnesium Stearate, Pregelatinized Maize Starch.

Dosage
1 - 2 tablets / day

WARNINGS:

• Do not exceed the recommended daily dose.

• S / D should not be used as a substitute for a balanced diet.

• Keep out of the reach of small children.

• This product is not intended to prevent, treat or cure any human disease.

• Check with your doctor if you are pregnant, breast-feeding, taking medication or have any health problems