Doctor's Formulas D-Mannose 60 capsules

Non-antibiotic Prophylaxis for Urinary Tract Infections
Urinary System Infections & Treatment

The formula D - Mannose is a dietary supplement containing the monosaccharide D-mannose.

What is D-Mannose? 

D-mannose is a simple sugar, which has a special contribution to metabolism, through its role in the glycosylation of certain proteins. D-mannose is rapidly absorbed and reaches the peripheral organs in about 30 minutes and is then excreted by the urinary system. It cannot be converted into glycogen, therefore, it is not stored in the body. It adheres to lectins and thus prevents the attachment of pathogenic organisms to the walls of the bladder.

Action mechanism 

Its mechanism of action is expressed through inhibition of adhesion of the surface protein FimH. By direct binding of FimH to D-mannose bound to a carrier protein, which is responsible for receptor specificity. 

 

The 1^ο adhesion step involves the mannose-sensitive binding of FimH to the epithelium. The bladder wall is coated with various mannose-glycosylated proteins, such as the Tamm-Horsfall protein (THP) that directly interferes with the adhesion of microbes to the mucosa. Tamm-Horsfall protein (THP) can bind to E. Coli by a specific bond, which can be inhibited by exogenous D-mannose.

 

By inhibiting the adhesion of microbes to the epithelium of the urinary tract, D-mannose mimics the function of the epithelial barrier of the urinary tract.

Suitable for vegetarians

EOF Notification Number: 47421 / 27-04-2018

(The Notification Number to the EOF is not a marketing authorization from the EOF)

EAN: 5200403400512

COMPOSITION IN NUTRITIONS	PER DAILY INSTALLMENT (1 to 2 capsules)
D - Mannose	500 --1000 mg

OTHER INGREDIENTS: magnesium stearate, gelatin, silicon dioxide.
(*) Does not contain preservatives, gluten, perfumes, sweeteners, etc.

Dosage
1 to 2 capsules per day

WARNINGS:

• Do not exceed the recommended daily dose.

• S / D should not be used as a substitute for a balanced diet.

• Keep out of the reach of small children.

• This product is not intended to prevent, treat or cure any human disease.

• Check with your doctor if you are pregnant, breast-feeding, taking medication or have any health problems.