Doctor's Formulas Vitamin D3 Liposomal Formula 150ml

The VITAMIN D3&K2 is a food supplement that contains the vitamins 2500 vitamin units D3 and 200 mcg of vitamin K2 (as menakinone-7 and specifically vitaMK7),

which contribute to maintaining:

• normal blood calcium levels 
• of the normal state of the bones

Liposomal shaping technology results in greater absorption and bioavailability of active substances and vitamins.

The liposomes

The liposomes belong to the colloidal dispersion of transport systems of bioactive molecules which have their transport capacity, improving their efficiency. The dimensions of the liposomes depending on the method of their preparation and the physicochemical characteristics of their structural units are in the order of nanometers up to the order of a few micrometers.

Historically, in the early 1960s, there was a tendency to study the biophysical properties of colloidal systems which had lipid and phospholipid composition, with the aim of understanding the biophysical functions of cells. Biophysicist AD Bangham studied lipid colloidal dispersions to simulate cell membranes and study their functionality.

Liposomes, since they are prepared from structural materials like those of our cells, have advantages related to thefriendlinessin terms of human tissues. They have the ability to transport lipophilic bioactive molecules which are not easily dissolved in aqueous media and therefore have problems of absorption and bioavailability, eg vitamins, curcumin, etc. but also water-soluble or amphiphilic molecules, improve their dissolution rate and absorption. through the gastrointestinal tract.

Liposomes can and do transport bioactive substances and improve their penetration through the barriers of the gastrointestinal tract and are effectivevehiclestransfer of bioactive molecules.

Η liposomal technology and especially the innovative technology of supramolecular phospholipid complexes with a lipid bilayer structure can improve the therapeutic efficacy of dietary supplements and are an innovation in this field, giving high added value to the final dosage form.

• The text was created in collaboration with the Laboratory of Pharmaceutical Nanotechnology of the Department of Pharmacy of the National and Kapodistrian University of Athens

• Bibliography: (1) K. Demetzos. Pharmaceutical Nanotechnology. Basic Principles and Practical Applications', Ed. Parisianou, 2014 (2) Y. Perrie, T. Rades 'Pharmaceutical Technology-Transportation and targeted action of drugs', Scientific Supervision K. Demetzos, Ed. Parisianou, 2016.